ASSOCIATION OF PHYTOCHEMICAL ANTIOXIDANTS INTAKE AND STRESS LEVEL IN HIGH SCHOOL STUDENTS IN KARAWANG
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Abstract
ABSTRACT
Phytochemical substances have been widely studied regarding their potential to deal with oxidative stress in the body, especially related to non-communicable disease prevention. However, research assessing the antioxidant potential of phytochemicals (flavonoids and carotenoids) in psychological stress is still very limited. This study aims to identify the relationship between flavonoid and carotenoid intake and stress levels in adolescents in Karawang. This research used a cross-sectional study of 103 students as respondents. Flavonoid and carotenoid intake was assessed using a 24-hour food recall, and stress levels were assessed using the DASS-42. The results of this study showed that 56.3 percent of respondents experienced moderate stress, 34.0 percent of respondents experienced mild stress and 9.7 percent of respondents experienced severe stress. The total intake of flavonoids in respondents in this study was only 35.61 ± 34.01 mg/day and the total intake of carotenoids was 2426.27 ± 2279.81 μg/day. This study did not find a relationship between total flavonoid intake and stress levels, but there was a significant relationship between β-cryptoxanthin, one of the carotenoid subclasses, and stress levels (p-value = 0.024). This study concluded that carotenoid intake had an influence on stress in respondents, but not flavonoid intake. Further research needs to identify antioxidant activity in the body to prevent increases in stress levels and reduce the impact of stress on adolescents.
Keywords: adolescent, antioxidants, dietary, stress
ABSTRAK
Substansi fitokimia telah banyak diteliti berkaitan dengan potensinya untuk menangani stress oksidatif dalam tubuh, terutama dalam kaitannya dengan pencegahan penyakit tidak menular. Namun, penelitian yang menilai potensi antioksidan fitokimia (flavonoid dan karotenoid) dalam kaitannya dengan stress psikologi masih sangat terbatas. Penelitian ini bertujuan untuk mengidentifikasi hubungan antara asupan flavonoid dan karotenoid dengan tingkat stress pada remaja di Karawang. Penelitian ini menggunakan cross-sectional study pada 103 siswa sebagai responden. Asupan flavonoid dan karotenoid dinilai menggunakan food recall 24 jam, dan tingkat stress dinilai menggunakan DASS-42. Hasil penelitian ini menunjukkan bahwa 56,3 percent responden mengalami stress tingkat sedang, 34,0 percent responden mengalami stress ringan dan 9,7 percent responden mengalami stress berat. Asupan total flavonoid pada responden penelitian ini hanya 35.61±34.01 mg/hari dan asupan total karotenoid sebesar 2426.27±2279.81μg/day. Penelitian ini tidak menemukan hubungan antara asupan total flavonoid dengan tingkat stress, tapi terdapat hubungan yang signifikan antara β-cryptoxanthin, salah satu subkelas karotenoid, dengan tingkat stress (p-value= 0,024). Penelitian ini menyimpulkan bahwa asupan karotenoid memiliki pengaruh terhadap stress pada responden, tapi tidak dengan asupan flavonoid. Penelitian selanjutnya perlu mengidentifikasi aktivitas aktioksidan dalam tubuh untuk mencegah peningkatan level stress dan mengurangi dampak akibat stress pada remaja.
Kata kunci: antioksidan, remaja, konsumsi pangan, stress
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References
Meeus W. Adolescent psychosocial development: A review of longitudinal models and research. Dev Psychol. 2016 Dec 1;52(12):1969–93.
Central Bureau of Statistics. Hasil Long Form Sensus Penduduk 2020. Jawa Barat; 2020.
Center for Reproductive Health U of Q, Johns Bloomberg Hopkins School of Public Health. I-NAMHS: Indonesia-National Adolescent Mental Health Survey. 2022.
Charlson F, van Ommeren M, Flaxman A, Cornett J, Whiteford H, Saxena S. New WHO prevalence estimates of mental disorders in conflict settings: a systematic review and meta-analysis. The Lancet. 2019 Jul 20;394(10194):240–8.
Lopresti AL. The Effects of Psychological and Environmental Stress on Micronutrient Concentrations in the Body: A Review of the Evidence. Vol. 11, Advances in Nutrition. Oxford University Press; 2020. p. 103–12.
Liu YZ, Wang YX, Jiang CL. Inflammation: The common pathway of stress-related diseases. Vol. 11, Frontiers in Human Neuroscience. Frontiers Media S. A; 2017.
Ouanes S, Popp J. High cortisol and the risk of dementia and alzheimer’s disease: A review of the literature. Vol. 11, Frontiers in Aging Neuroscience. Frontiers Media S.A.; 2019.
Marsland AL, Walsh C, Lockwood K, JohnHenderson NA. The effects of acute psychological stress on circulating and stimulated inflammatory markers: A systematic review and meta analysis. Brain Behav Immun. 2017 Aug 1;64:208–19.
Wirtz PH, von Känel R. Psychological Stress, Inflammation, and Coronary Heart Disease. Vol. 19, Current Cardiology Reports. Current Medicine Group LLC 1; 2017.
Lagraauw HM. Stress-induced modulation of innate immune system in cardiovascular disease.
Liu X, Cao H, Zhu H, Zhang H, Niu K, Tang N, et al. Association of chronic diseases with depression, anxiety and stress in Chinese general population: The CHCNBTH cohort study. J Affect Disord. 2021 Mar 1;282:1278–87.
Chen X, Orom H, Hay JL, Waters EA, Schofield E, Li Y, et al. Differences in Rural and Urban Health Information Access and Use. Journal of Rural Health. 2019 Jun 1;35(3):405–17.
Mazidi M, Katsiki N, Banach M. A greater flavonoid intake is associated with lower total and cause-specific mortality: A meta analysis of cohort studies. Nutrients. 2020 Aug 1;12(8):1–14.
Ayoka TO, Ezema BO, Eze CN, Nnadi CO. Antioxidants for the Prevention and Treatment of Non-communicable Diseases. J Explor Res Pharmacol. 2022 Jul 6;000(000):000–000.
Bhagwat S, Haytowitz DB, Wasswa-Kintu SI, Holden JM. USDA Develops a Database for Flavonoids to Assess Dietary Intakes. Procedia Food Sci. 2013;2(Idb 2):81–6.
Sefrina LR, Briawan D, Sinaga T, Permaesih D. Flavonoid database based on Indonesian foods. J Nutr Sci Vitaminol (Tokyo). 2020;66.
Andarwulan N, Puspita NC, Saraswati, Średnicka-Tober D. Antioxidants such as flavonoids and carotenoids in the diet of Bogor, Indonesia residents. Antioxidants. 2021 Apr 1;10(4).
Al-Khayri JM, Sahana GR, Nagella P, Joseph B V., Alessa FM, Al-Mssallem MQ. Flavonoids as Potential Anti-Inflammatory Molecules: A Review. Vol. 27, Molecules. MDPI; 2022.
Leyva-López N, Gutierrez-Grijalva EP, Ambriz-Perez DL, Basilio Heredia J. Flavonoids ascytokine modulators: A possible therapy for inflammation-related diseases. Vol. 17, International Journal of Molecular Sciences. MDPI AG; 2016.
Hajizadeh-Sharafabad F, Zahabi ES, Malekahmadi M, Zarrin R, Alizadeh M. Carotenoids supplementation and inflammation: a systematic review and meta-analysis of randomized clinical trials. Vol. 62, Critical Reviews in Food Science and Nutrition. Taylor and Francis Ltd.;
p. 8161–77.
Richard A, Rohrmann S, Vandeleur CL, Mohler-Kuo M, Eichholzer M. Associations between fruit and vegetable consumption and psychological distress: Results from a population-based study. BMC Psychiatry. 2015 Oct 1;15(1).
Nguyen B, Ding D, Mihrshahi S. Fruit and vegetable consumption and psychological
distress: cross-sectional and longitudinal analyses based on a large Australian sample.
Saghafian F, Malmir H, Saneei P, Milajerdi A, Larijani B, Esmaillzadeh A. Fruit and vegetable consumption and risk of depression: Accumulative evidence from an updated systematic review and metaAnalysis of epidemiological studies. Vol. 119, British Journal of Nutrition. Cambridge University Press; 2018. p. 1087–101.
Głąbska D, Guzek D, Groele B, Gutkowska K. Fruit and vegetable intake and mental health in adults: A systematic review. Vol. 12, Nutrients. MDPI AG; 2020.
Samad N, Saleem A, Yasmin F, Shehzad MA. Quercetin protects against stress induced anxiety- and depression- like behavior and improves memory in male mice. Physiol Res. 2018;67(5):795–808.
Lin S, Shen Y. Dietary carotenoids intake and depressive symptoms in US adults, NHANES 2015–2016. J Affect Disord. 2021 Mar 1;282:41–5.
Unno K, Noda S, Nii H, Kawasaki Y, Iguchi K, Yamada H. Anti-stress Effect of β Cryptoxanthin
in Satsuma Mandarin Orange on Females. Vol. 42, Biol. Pharm. Bull. 1402.
Abshirini M, Siassi F, Koohdani F, Qorbani M, Mozaffari H, Aslani Z, et al. Dietary total
antioxidant capacity is inversely associated with depression, oxidative stress anxiety and some biomarkers in postmenopausal women: a cross-sectional study. Ann Gen Psychiatry. 2019 Dec
;18(1).
Karawang Central Bureau of Statistic. Karawang in Numbers Year 2023. 2023 Feb.
Ke JY, Cole RM, Hamad EM, Hsiao YH, Cotten BM, Powell KA, et al. Citrus flavonoid, naringenin, increases locomotor activity and reduces diacylglycerol accumulation in skeletal muscle of obese ovariectomized mice. Mol Nutr Food Res. 2016 Feb 1;60(2):313–24.
Kalkan Uğurlu Y, Mataracı Değirmenci D, Durgun H, Gök Uğur H. The examination of the relationship between nursing students’ depression, anxiety and stress levels and restrictive, emotional, and external eating behaviors in COVID-19 social isolation process. Perspect Psychiatr Care. 2021 Apr 1;57(2):507–16.
Sefrina LR, Briawan D, Sinaga T, Permaesih D. Estimasi Asupan Karotenoid pada Usia Dewasa di Indonesia. Jurnal Gizi dan Pangan. 2017 Mar;12(1):1–8.
USDA National Nutrient Database for Standard ReferenceRelease 28.
Boozari B, Moradi S, Heydarpour F, Clark CCT, Nezamoleslami S, Saneei P, et al. The association between carotenoid intake, mental health, and sleep quality among university students. Sleep and Breathing. 2022 Jun 1;26(2):829–37.
Rucklidge JJ, Kaplan BJ, Mulder RT. What if nutrients could treat mental illness? Vol. 49, Australian and New Zealand Journal of Psychiatry. SAGE Publications Ltd; 2015. p. 407–8.
Abshirini M, Siassi F, Koohdani F, Qorbani M, Mozaffari H, Aslani Z, et al. Dietary total antioxidant capacity is inversely associated with depression, oxidative stress anxiety and some biomarkers in postmenopausal women: a cross-sectional study. Ann Gen Psychiatry. 2019 Dec 1;18(1).
Richard A, Rohrmann S, Vandeleur CL, Mohler-Kuo M, Eichholzer M. Associations between fruit and vegetable consumption and psychological distress: Results from a population-based study. BMC Psychiatry. 2015 Oct 1;15(1).
Nguyen B, Ding D, Mihrshahi S. Fruit and vegetable consumption and psychological distress: cross-sectional and longitudinal analyses based on a large Australian sample. Available from: http://dx.doi.org/10.1136/bmjopen-2016014201
Głąbska D, Guzek D, Groele B, Gutkowska K. Fruit and vegetable intake and mental health in adults: A systematic review. Vol. 12, Nutrients. MDPI AG; 2020.
Health Ministry of Indonesia. Guidance of Balanced Nutrition. Kesehatan RI. 2014. 97 p. Kementerian
Richard A, Rohrmann S, Vandeleur CL, Mohler-Kuo M, Eichholzer M. Associations between fruit and vegetable consumption and psychological distress: Results from a population-based study. BMC Psychiatry. 2015 Oct 1;15(1).
Sefrina LR, Rahmatunisa R. Estimation of Total Dietary Flavonoid Intake on Health and Non-Health Students in Karawang. 2020;1(September):18–24.
Escobar‐Cévoli R, Castro‐Espín C, Béraud V, Buckland G, Zamora‐Ros R. An Overview of Global Flavonoid Intake and its Food Sources. In: Flavonoids - From Biosynthesis to Human Health. InTech; 2017.
Vogiatzoglou A, Mulligan AA, Lentjes MAH, Luben RN, Spencer JPE, Schroeter H, et al. Flavonoid Intake in European Adults (18 to 64 Years). 2015;
Haidari F, Hojhabrimanesh A, Helli B, Seyedian SS, Ahmadi-Angali K, Abiri B. A hypocaloric high-protein diet supplemented with β-cryptoxanthin improves non-alcoholic fatty liver disease: a randomized controlled trial. BMC Gastroenterol. 2020 Dec 1;20(1).
Iwamoto M, Imai K, Ohta H, Shirouchi B, Sato M. Supplementation of highly concentrated β cryptoxanthin in a satsuma mandarin beverage improves adipocytokine profiles in obese Japanese women. Lipids Health Dis. 2012;11.
Unno K, Noda S, Nii H, Kawasaki Y, Iguchi K, Yamada H. Anti-stress Effect of β Cryptoxanthin in
Satsuma Mandarin Orange on Females. Vol. 42, Biol. Pharm. Bull. 1402.
Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Yano M. High serum carotenoids associated with lower risk for the metabolic syndrome and its components among Japanese subjects: Mikkabi cohort study. British Journal of Nutrition. 2015 Oct 5;114(10):1674–82.
Sugiura M, Nakamura M, Ogawa K, Ikoma Y, Yano M. High serum carotenoids are associated with lower risk for developing elevated serum alanine aminotransferase among Japanese subjects: The Mikkabi cohort study. British Journal of Nutrition. 2016 Apr 28;115(8):1462–9.
Choi J. Impact of stress levels on eating behaviors among college students. Nutrients. 2020 May 1;12(5).
Emond M, Ten Eycke K, Kosmerly S, Robinson AL, Stillar A, Van Blyderveen S. The effect of academic stress and attachment stress on stress-eaters and stress-undereaters. Appetite. 2016 May 1;100:210–5.
Lee G, Han K, Kim H. Risk of mental health problems in adolescents skipping meals: The Korean National Health and Nutrition Examination Survey 2010 to 2012. Nurs Outlook. 2017 Jul 1;65(4):411–9.
Gambaran Faktor Risiko Penyakit Tidak Menular Siswa MAN 02 Mukomuko. Scientific Journal. 2023;II(3):103–9.
Daneshzad E, Keshavarz SA, Qorbani M, Larijani B, Azadbakht L. Dietary total antioxidant capacity and its association with sleep, stress, anxiety, and depression score: A cross-sectionalstudy among diabetic women. Clin Nutr ESPEN. 2020 Jun 1;37:187–94.
Fedoce A das G, Ferreira F, Bota RG, Bonet-Costa V, Sun PY, Davies KJA. The role of oxidative stress in anxiety disorder: cause or consequence? Vol. 52, Free Radical Research. Taylor and Francis Ltd; 2018. p. 737–50.
Salim S. Oxidative stress: a potential link between emotional wellbeing and immune response. Vol. 29, Current Opinion in Pharmacology. Elsevier Ltd; 2016. p. 70–6.
Farhadnejad H, Neshatbini Tehrani A, Salehpour A, Hekmatdoost A. Antioxidant vitamin intakes and risk of depression, anxiety and stress among female adolescents. Clin Nutr ESPEN. 2020 Dec 1;40:257–62.
Ragelienė T, Grønhøj A. The influence of peers′ and siblings′ on children’s and adolescents′ healthy eating behavior. A systematic literature review. Appetite. 2020 May 1;148.