PENGARUH SUPLEMENTASI MULTIVITAMIN MINERAL TERHADAP STATUS GIZI DAN KESEHATAN

Abstract

THE EFFECT OF MULTIVITAMIN MINERAL SUPPLEMENTATION
ON NUTRITIONAL STATUS AND HEALTH

Use of multivitamin mineral (MVM) supplement has grown rapidly over the past several decades.
According to several studies, supplement users tend to have higher micronutrient intakes from their
diet than nonusers. Consequently, they have an increased intake but are also more likely to exceed
the upper level. The study was aimed to analyze the effect of MVM supplementation on renal function
through the double blind randomized controlled trial. Subjects were 93 of the female workers in PT
Ricky Putra Globalindo Tbk, Citeureup, Bogor who were randomly allocated to three treatments. The
first received only placebo (without vitamin C and MVM); the second received 1000 mg vitamin C; and
the third received MVM supplement that contains 1000 mg vitamin C, 45 mg vitamin E, 700 µg vitamin
A, 6,5 mg vitamin B6, 400 µg folic acid, 9,6 µg vitamin B12, 10 µg vitamin D, 10 mg Zn, 110 µg Se, 0,9
mg Cu, and 5 mg Fe. The supplements were distributed and consumed daily during 10 weeks. The
mean change before and after study were tested with t paired test. The results showed the BMI,
systolic and diastolic blood pressure, urea and creatinine blood serum were not significantly different
before and after study (p>0,05). The distribution of female workers based on BMI showed that more
than half of them have normal nutritional status (BMI 18,5-24,9 kg/m
2
). The distribution based on
systolic and diastolic blood pressure showed that most of them were not hypertension (systolic <140
mmHg, diastolic <90 mmHg); and the distribution based on urea and creatinine showed that most of
them have normal status (urea 8,0-25,0 mg/dl; creatinine 0,6-1,5 mg/dl).

Keywords: food supplement, BMI, blood pressure, urea, creatinine.